An Indian-origin researcher in the UK is developing an adjustable artificial lens, made from the same material found in smartphone and TV screens, which could improve vision in older people with presbyopia and cataracts.
Controlling presbyopia
As people age, their lenses lose flexibility and elasticity. This leads to a condition known as presbyopia, common in people over 45 years old, and can require optical aids, such as reading glasses. Devesh Mistry, a postgraduate research student in the School of Physics and Astronomy, at the University of Leeds is working with liquid crystal to create a truly adjustable artificial lens. "As we get older, the lens in our eye stiffens, when the muscles in the eye contract they can no longer shape the lens to bring close objects into focus," he said.
"Using liquid crystals, which we probably know better as the material used in the screens of TVs and smartphones, lenses would adjust and focus automatically, depending on the eye muscles' movement," he added. Using these liquid crystal-based materials, Mistry's research is developing synthetic replacements for the diseased lens in the eye - a new generation of lenses and intra-ocular lens implants to rejuvenate sight.
Devesh is sure that the condition can be cured by using liquid crystals - a material that is not a solid, liquid or a gas but is in the fourth state of matter.
Liquid crystals are structured like a crystal, but its properties can be changed by mechanical or electrical force. It is used in TV and smartphone screens.
The new lens could be inserted into the eye in a quick operation with the application of local anesthetic, similar to how cataracts are currently inserted.
The eye surgeon would make destroy the old lens and replace it with the new one made of liquid crystal.
The prototype goes live in 2018
Mistry is currently researching and developing the lens in the lab and aims to have a prototype ready by the end of his doctorate in 2018. Within a decade, the research could see the new lens being implanted into eyes in a quick and straightforward surgical procedure under local anaesthetic. Eye surgeons would make an incision in the cornea and use ultrasound to break down the old lens. The liquid crystal lens would then be inserted, restoring clear vision. The lens could also have application in tackling cataracts - the clouding of natural lenses - which affect many people in later life and which can seriously affect vision. A common treatment is to remove and replace the natural lens.
"Liquid crystals are a very under-rated phase of matter," Mistry told 'The Times'.
"Everybody's happy with solids, liquids and gases and the phases of matter, but liquid crystals lie between crystalline solids and liquids. They have an ordered structure like a crystal, but they can also flow like a liquid and respond to stimuli," he said. Mistry is working in collaboration with the Eurolens Research at the University of Manchester and with UltraVision CLPL, a specialist contact lenses manufacturer headed by two University of Leeds alumni. His research builds upon previous work by the same collaborators, who developed a prototype contact lens with an electrically-controllable focus using liquid crystals. The first commercially-available liquid crystal lenses could be on sale between six and ten years' time.